Idiopathic Crescentic Glomerulonephritis or Systemic Vasculitis?

Pauci-Immune Crescentic Glomerulonephritis: An ANCA-Associated Vasculitis

Rapidly progressive glomerulonephritis (RPGN) is a syndrome signified by a precipitous loss of renal function, with features of glomerulonephritis including dysmorphic erythrocyturia and glomerular proteinuria. RPGN is associated with extensive crescent formation, and, thus, the clinical term RPGN is often used interchangeably with the pathologic term crescentic glomerulonephritis (CGN). From a...

A Case of Crescentic Glomerulonephritis Complicated with Hypocomplementemic Urticarial Vasculitis Syndrome and ANCA-Associated Vasculitis

Systemic urticaria in a 64-year-old woman was diagnosed as leukocytoclastic vasculitis by a punch biopsy of the skin. Her physical findings improved after prescription of prednisolone at a dose of 20 mg/day, but the skin rash relapsed with renal dysfunction, proteinuria, and hematuria when the dose of prednisolone was reduced over a period of 9 months to 1 mg/day. She was admitted to our instit...

T cells in crescentic glomerulonephritis.

Crescent formation in glomerulonephritis (GN) is a manifestation of severe glomerular injury that usually results in a poor clinical outcome. In humans, crescentic GN is frequently associated with evidence of either systemic or organ-specific autoimmunity. T cells play a major role in initiation of adaptive immune responses that lead to crescentic injury. In experimental models of crescentic GN...

Crescentic glomerulonephritis and centrocytic lymphoma.

Necrotizing-crescentic glomerulonephritis in ANCA-associated vasculitis: the role of monocytes.

role in inflammatory processes, acting directly or in Introduction concert with other arms of the immune system. According to previous studies, both in human and ANCA-associated renal vasculitis ( Wegener’s granuloexperimental models and according to our permatosis, Microscopic polyarteritis and its renal limited sonal experience, we firmly believe that monocytevariant) are morphologically char...